Question

A “pyridine-enhanced” NHC catalyst system for these reactions contains an alpha-donating 3-chloropyridine (-5[1])group, as well as a bulky IPr ligand. For these reactions, the Organ group created stable PEPPSI catalysts. Many catalysts for these reactions contain the ferrocene ligand dppf. (15[1])Nonaflates (“NON-uh-flates”) and triflates are useful electrophiles for these reactions. It is difficult to perform most of these reactions with alkyl compounds in water due to (*) beta-hydride elimination side reactions. One of these reactions used to synthesize substituted biphenyls uses a catalyst with a transition metal and four triphenylphosphine groups. These reactions (10[1])go through a (-5[1])catalytic cycle of oxidative (-5[1])addition, transmetalation, (10[2])and reductive (10[1])elimination steps. For 10 points, name this class of reactions that uses a palladium(0) catalyst to form carbon–carbon bonds, such as one named for Suzuki. ■END■ (10[2]0[8])

Buzzes

Summary