Question

Note to moderator: Read answerline carefully. Since its 2005 FDA approval, a prodrug that competes with one of these compounds has been added to chemotherapy regimens to noticeably increase survival from T-cell acute lymphoblastic leukemia. NBMPR inhibits a bidirectional transporter of these compounds, a family of which, exemplified by SLC28, uses a sodium gradient to move these compounds [emphasize] against their concentration. The pancreatic cancer drug gemcitabine is imported by transceptors that act on these (-5[1])compounds, which in humans are classified as either (*) “concentrative” or “equilibrative.” The kinases TK1 and NME triply phosphorylate an antiviral drug resembling one of these (-5[1])compounds with a 3-prime azido group replacing a (10[1])hydroxyl. A family of reverse (-5[1])transcriptase inhibitors, exemplified by (10[1]-5[2])AZT, disrupt DNA (-5[1])replication by acting as analogues of these compounds. For 10 points, name these phosphate-lacking metabolites consisting of a five-carbon sugar and a (10[1])nitrogenous base. (10[7]0[4])■END■

ANSWER: nucleosides [accept nucleoside analog reverse transcriptase inhibitors or nucleoside transporter; prompt on nucleobases; prompt on purines or pyrimidines; prompt on hENTs or hCNTs; reject “nucleotides” or “nucleic acids”]
<RH, Biology>
= Average correct buzz position

Buzzes

PlayerTeamOpponentBuzz PositionValue
Billy BusseBHSU BA Nervy Liberal Nanny Hence74-5
Andrew WangPunished "Venom" BHSUit's the great pumpkinification objection, charlie brown99-5
Eric MukherjeeLMM's LLM MLMThe Dyatlov Passement incident10710
June YinLes Missourablesvar merchants112-5
Kevin WanggenAI this, genAI that, have you found your 真爱 yetFirst Cause, First Cause, make me young!116-5
Walter ZhaoRead slowly: A A A A A A A A A A A A A A A Read quickly: AAre You There, Chat? It's Me, Margaret11610
Daniel MaThere are buzzable clues everywhere for those with eyes to seeLisan al-Quib116-5
Arya KarthikCharlotte's Moderately Successful TeamNJTRANSit (and bobby, i guess)119-5
Gautam Kandlikarwhen you look this good, you don’t have to know anythingMindgoblin of Little Hobbes14110
Annabelle YangA Nervy Liberal Nanny HenceBHSU B14310
Sky HongNJTRANSit (and bobby, i guess)Charlotte's Moderately Successful Team1430
Richard NiuAMOGH QUIZ HACK? 英雄联盟 400 PPG 24 TUHGalvanized Square Steen and Eco-Friendly Wood Vermeer14310
Nikhil DesaiFirst Cause, First Cause, make me young!genAI this, genAI that, have you found your 真爱 yet14310
Gareth ThorlaksonThe Empire Bikes BackI’ll take a quiet 10 / A handshake of CO (Chicago Open)1430
Jeremy TsaiI’ll take a quiet 10 / A handshake of CO (Chicago Open)The Empire Bikes Back14310
Rahul KeyalLying on a Mattress at Lou’s Apartment in Pilsen, ChicagoThe Oldest Men in the World1430
Alex AkridgeWe Need New Namessticking out your guyot for the ridge push; you're so seafloor spread, you're so fracture zone14310
Jason HongThe Jeam TeamNJTRANSit (and anwen, I guess)14310
Natan HoltzmanLisan al-QuibThere are buzzable clues everywhere for those with eyes to see14310
Rohan Khervar merchantsLes Missourables1430

Summary

TournamentEditionExact Match?TUHConv. %Power %Neg %Average Buzz
2024 Chicago Open07/28/2024Y1471%0%43%136.50