Question

Starting at embryonic day 9.5, development of a subset of these cells is driven by Pax1 expression, and these cells also require Hoxa3 after day 11 for sustained growth. One class of these cells uses the zinc finger protein FezF2 to help carry out a “promiscuous” process with adjacent developing cells. Transgenic mice for studying these cells are frequently controlled by a Foxn1 promoter. Deficiencies in at least one class of these cells will impair formation of (*) Hassall’s corpuscles. A mature class of these cells presents tissue-restricted antigens to one class (-5[1])of developing lymphocytes (-5[2])via the protein AIRE. (10[1])That (-5[1])class of these cells is named for their location in the medulla of a naturally involuting organ, as opposed to their cortical counterparts (-5[1])that regulate positive selection. For 10 points, name these stromal cells from a namesake organ (-5[1])that mediate multiple (10[1])key steps in T-cell development. ■END■ (10[1]0[7])

ANSWER: thymic epithelial cells [or medullary thymic epithelial cells; or cortical thymic epithelial cells; or thymus epithelial cells; accept TECs (“teks”); accept mTECs (“M-teks”) or cTECs (“C-teks”); accept junctional thymic epithelial cells or jTECs (“J-teks”); accept thymic tuft cells; prompt on epithelial cells by asking “in which organ?”] (The clues in order refer to: thymic tuft cells, mTECs, PGE and AIRE+ mTECs, all TECs broadly, jTECs/mTECS, just mTECs, cTECs, TECs generally.)
<RH, Biology>
= Average correct buzz position

Buzzes

PlayerTeamOpponentBuzz PositionValue
Iain CarpenterAre You There, Chat? It's Me, MargaretLisan al-Quib90-5
Eric MukherjeeLMM's LLM MLMwhen you look this good, you don’t have to know anything93-5
Billy BusseBHSU BThere are buzzable clues everywhere for those with eyes to see93-5
Adam Finesticking out your guyot for the ridge push; you're so seafloor spread, you're so fracture zoneThe Dyatlov Passement incident9710
Andrew WangPunished "Venom" BHSUvar merchants98-5
Walter ZhaoRead slowly: A A A A A A A A A A A A A A A Read quickly: ALying on a Mattress at Lou’s Apartment in Pilsen, Chicago121-5
Rasheeq AzadMindgoblin of Little HobbesNJTRANSit (and bobby, i guess)136-5
Annabelle YangA Nervy Liberal Nanny HenceThe Empire Bikes Back13910
Isaac Kirk-DavidoffFirst Cause, First Cause, make me young!AMOGH QUIZ HACK? 英雄联盟 400 PPG 24 TUH1450
Richard NiuAMOGH QUIZ HACK? 英雄联盟 400 PPG 24 TUHFirst Cause, First Cause, make me young!1450
Gautam Kandlikarwhen you look this good, you don’t have to know anythingLMM's LLM MLM1450
Sky HongNJTRANSit (and bobby, i guess)Mindgoblin of Little Hobbes1450
Eve Fleisigit's the great pumpkinification objection, charlie brownNJTRANSit (and anwen, I guess)1450
Fierro GreyNJTRANSit (and anwen, I guess)it's the great pumpkinification objection, charlie brown1450
Colin Stewartvar merchantsPunished "Venom" BHSU1450
Chris RayWe Need New NamesgenAI this, genAI that, have you found your 真爱 yet14510

Summary

TournamentEditionExact Match?TUHConv. %Power %Neg %Average Buzz
2024 Chicago Open07/28/2024Y1127%0%55%127.00